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AP Top News at 12:57 a.m. EDT

AP-GfK Poll: Clinton appears on cusp of commanding victory
NEW YORK (AP) - Hillary Clinton appears on the cusp of a potentially commanding victory over Donald Trump, fueled by solid Democratic turnout in early voting, massive operational advantages and increasing enthusiasm among her supporters. A new Associated Press-GfK poll released Wednesday finds that Clinton has grabbed significant advantages over her Republican rival with just 12 days left before Election Day. Among them: consolidating the support of her party and even winning some Republicans. "I'm going to pick Hillary at the top and pick Republican straight down the line," said poll respondent William Goldstein, a 71-year-old from Long Island, New York, who voted for Mitt Romney in 2012.

Trump: I'll run America like my business. Clinton: Let's not
WASHINGTON (AP) - His presidential dreams increasingly in question, Donald Trump pushed his business empire to the center of his political campaign Wednesday. Taking a break from battleground states, he made the case at his newest hotel that all Americans should look to his corporate record for evidence of how well he'd run the country. "Under budget and ahead of schedule. So important. We don't hear those words so often, but you will," said Trump, linking the hotel redevelopment - just blocks from the White House - to his promised performance as president. "Today is a metaphor for what we can accomplish for this country."

Large anti-Maduro protests fill the streets in Venezuela
CARACAS, Venezuela (AP) - Anti-government protesters filled the streets of Venezuela's capital and other major cities in a show of force against Presidential Nicolas Maduro, whose allies enraged the opposition by blocking a recall referendum against the socialist leader. Tens of thousands of demonstrators shut down Caracas' main highway on Wednesday, many chanting "Democracy yes! Dictatorship no!" And police clashed with protesters in other cities in what opposition leaders called "the takeover of Venezuela." Nationwide at least 140 people were detained by police, according to the Foro Penal human rights group. A police officer was shot and killed, and two others injured, under unclear circumstances in central Miranda state.

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2 quakes rattle Italy, crumbling buildings and causing panic
ROME (AP) - A pair of strong aftershocks shook central Italy late Wednesday, crumbling churches and buildings, knocking out power and sending panicked residents into the rain-drenched streets just two months after a powerful earthquake killed nearly 300 people. But hours after the temblors hit, there were no reports of serious injuries or signs of people trapped in rubble, said the head of Italy's civil protection agency, Fabrizio Curcio. A handful of people were treated for slight injuries or anxiety at area hospitals in the most affected regions of Umbria and Le Marche, he said. A 73-year-old man died of a heart attack, possibly brought on by the quakes, local authorities told the ANSA news agency.

French authorities declare the Calais migrant camp empty
CALAIS, France (AP) - The grim camp known as "the jungle," a symbol of Europe's failure to come to grips with its crisis over asylum seekers, is no more. French authorities declared Wednesday they had cleared out the camp after most of its thousands of residents were driven away on buses - an evacuation accelerated because some of the frustrated, departing migrants set fire to parts of the burgeoning slum. Smoke hung in the air as dusk fell, its stench a reminder of how one of the world's wealthiest nations was unable to create order at the camp, where those fleeing war and poverty have lived in squalor for months or longer.

Tense standoff at Dakota Access protest encampment
CANNON BALL, N.D. (AP) - The prospect of a police raid on an encampment protesting the Dakota Access pipeline faded as night fell Wednesday, with law enforcement making no immediate move after protesters rejected their request to withdraw from private land. Unmarked aircraft that had been monitoring protesters were withdrawn late in the day, and some activists who had been on hand for a possible confrontation headed back to a larger protest camp on federal land. Law enforcement officials said they were ready to remove about 200 protesters who this weekend set up teepees and tents on land owned by the pipeline company.

Patients left in limbo as more doctors flee Puerto Rico
SAN JUAN, Puerto Rico (AP) - Wanda Serrano arrived at Puerto Rico's largest public hospital before dawn to take her 17-year-old son to an appointment. Six hours later, they were still in the packed waiting room hoping to see a doctor. They had gone to San Juan's Centro Medico to see one of the many kinds of specialists the teen needs for treatment of a genetic disease called tuberous sclerosis, which can cause tumors to grow on his brain, kidneys and other organs. But specialized medical expertise is increasingly difficult to find in the economically troubled U.S. island territory. Six hours in a waiting room is no longer the exception, but the norm.

Weed as way of life: California farmers divided on legal bud
GARBERVILLE, Calif. (AP) - Laura Costa's son and husband moved quickly with the pruning shears to harvest the family's fall marijuana crop, racing along with several workers to cut the plants and drop them in plastic bins ahead of an impending storm. The rain could invite "bud rot," Costa said, "a big no-no." The farm, hidden along a winding mountain road in a remote redwood forest, is just one of many illegal "grows" that make up Northern California's famous Emerald Triangle, a rural region that developed over decades into a marijuana-producing mecca at the intersection of Humboldt, Mendocino and Trinity counties.

Wal-Mart pushes service for holiday; Target stresses value
TETERBORO, N.J. (AP) - Wal-Mart, long known for emphasizing low prices, wants to be known this holiday season for superior customer service. That comes after its main rival Target, which has a better image in that regard, stressed a focus on offering deals. The world's largest retailer plans to deploy "holiday helpers" stationed at the checkouts, who can direct customers to registers with shorter lines or even run back to the aisles to pick up an item a customer forgot. The ways in which Target and Wal-Mart are each trying to be more like the other underscore how traditional retailers have to raise their game in every aspect as shoppers who could easily shop online instead become more demanding about price, selection and service.

Arrieta deals, Cubs awaken, top Indians to even Series at 1
CLEVELAND (AP) - Jake Arrieta made a teasing try at history, Kyle Schwarber drove in two runs and the Chicago Cubs brushed off a shutout to even the World Series with their first Fall Classic win in 71 years, 5-1 over the Cleveland Indians in Game 2 on Wednesday night. Arrieta carried a no-hitter into the sixth inning, briefly invoking Don Larsen's name, before the Indians touched him for two hits and a run. However, the right-hander helped give Chicago just what it needed - a split at Progressive Field - before the Cubbies return to their Wrigley Field den for the next three games starting Friday night.