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AP Top Political News at 3:54 a.m. EDT

Trump heading to Mexico ahead of immigration speech
EVERETT, Washington (AP) -- Donald Trump will be taking his first foreign trip as the Republican presidential nominee on Wednesday, making a quick visit to Mexico, a nation he derided as the home of rapists and criminals as he launched his campaign....

McCain defeats Republican challengers to win Arizona primary
PHOENIX (AP) -- Sen. John McCain beat back a primary challenge Tuesday from a Republican tea party activist to win the right to seek a sixth term in November in a race that has been inundated with questions about GOP presidential candidate Donald Trump....

After easy win, Rubio has bigger challenge to keep seat
TALLAHASSEE, Fla. (AP) -- Republican Sen. Marco Rubio's presidential aspirations and insistence that he was done with the Senate didn't hurt him with GOP voters, now it's time to see if the rest of Florida will be as forgiving as he seeks a second term....

Metro Phoenix's sheriff wins primary in bid for 7th term
PHOENIX (AP) -- The sheriff for metropolitan Phoenix trounced three rivals Tuesday to win his Republican primary in what could be the toughest campaign in his 24 years in office as he faces a storm of legal troubles stemming from his immigration patrols....

Questions Trump may tackle in anticipated immigration speech
SEATTLE (AP) -- After an unexpected visit to Mexico on Wednesday, Donald Trump is set to deliver a much-anticipated speech on immigration in Arizona. He'll do so under pressure to clarify where he stands on the finer points of an issue that's defined his campaign for president....

Obama cuts short the sentences of 111 federal inmates
WASHINGTON (AP) -- President Barack Obama cut short on Tuesday the sentences of 111 federal inmates in another round of commutations for those convicted of nonviolent drug offenses....

Feds to distribute $53 million to states to fight opioids
WASHINGTON (AP) -- The Obama administration says it will distribute $53 million to 44 states in an effort to curb opioid abuse....

Suicidal Germanwings pilot had struggled in US flight school
WASHINGTON (AP) -- The German pilot who deliberately flew his airliner into a mountainside last year had struggled with learning to fly and had failed a key test of his skills during training in the U.S., according to FBI interviews with his flight instructors....

The Latest: Trump says immigrants taking minorities' jobs
WASHINGTON (AP) -- The Latest on the U.S. presidential race (all times EDT):...

WHY IT MATTERS: The Role of Government
WASHINGTON (AP) -- THE ISSUE: It's the Goldilocks conundrum of American politics: Is the federal government too big, too small or just right?...

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