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AP Top U.S. News at 4:30 a.m. EDT

Senate health care deal in doubt as Trump says he's opposed
WASHINGTON (AP) -- A bipartisan Senate deal to curb the growth of health insurance premiums is reeling after President Donald Trump reversed course and opposed the agreement and top congressional Republicans and conservatives gave it a frosty reception....

Judge: Newest travel ban 'same maladies' as previous version
HONOLULU (AP) -- Just hours before President Donald Trump's latest travel ban was to take full effect, a federal judge in Hawaii blocked the revised order, saying the policy has the same problems as a previous version....

Big question for US cities: Is Amazon's HQ2 worth the price?
WASHINGTON (AP) -- Dozens of cities are working frantically to land Amazon's second headquarters, raising a weighty question with no easy answer:...

Amazon has brought benefits - and disruption - to Seattle
SEATTLE (AP) -- Memo to the many places vying for Amazon's second headquarters: It ain't all food trucks and free bananas....

Wooing Amazon with sun, fun ... and giant buttons
BOSTON (AP) -- Mayors from Toledo to Tulsa are so eager to woo Amazon's much-vaunted second headquarters that they're brandishing bourbon, selling the sun, whispering sweet nothings to the company and even pushing its buttons....

US Rep: Trump says fallen soldier knew what he signed up for
MIAMI (AP) -- President Donald Trump told the widow of a slain soldier that he "knew what he signed up for," according to a Florida congresswoman....

Ultra-personal therapy: Gene tumor boards guide cancer care
SAN DIEGO (AP) -- Doctors were just guessing a decade ago when they gave Alison Cairnes' husband a new drug they hoped would shrink his lung tumors. Now she takes it too, but the choice was no guesswork. Sophisticated gene tests suggested it would fight her gastric cancer, and they were right....

Up in smoke: Wildfires scorch California pot crop at harvest
GLEN ELLEN, Calif. (AP) -- Desperate to see if wildfires had damaged his farm, Marcos Morales gunned his four-wheel-drive station wagon along the hidden dirt roads that crisscross Sonoma County vineyards....

Tough housing market awaits California wildfire victims
PETALUMA, Calif. (AP) -- The many thousands who lost their houses, condos and apartments in wildfires burning in Northern California will have to find a new place to live in one of the toughest housing markets in the nation....

Jefferson told lawyers to read these; now they'll be online
CHARLOTTESVILLE, Va. (AP) -- Thick tomes on the laws of England. Half a dozen legal dictionaries. Books on Roman law and maritime law....

AP Photo
AP Photo/Andrew Harnik
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Up to the Minute
Trial delayed for 'cocaine cowboy' on the run for 26 years

Jefferson told lawyers to read these; now they'll be online

Up in smoke: Wildfires scorch California pot crop at harvest

Houston-area "Tourniquet Killer" set to die

The Latest: Southern California fire partially contained

Vegas hotel security guard's disappearance draws attention

Colorado teen killed young siblings to be alone, police say

Utility scrutinized as California wildfire victims sue

Kentucky city begins moving 2 Confederate statues

Lawyers drop out of landlord's appeal in fire that killed 6

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