DENVER (AP) -- Michael Cuddyer hit a grand slam and drove in a career-high seven runs, leading the Colorado Rockies to a 15-3 victory over the Arizona Diamondbacks on Friday night.
Jordan Lyles pitched six strong innings for his first win in six weeks.
Rafael Ynoa added four hits and three RBIs and Wilin Rosario had three hits and two RBIs for the Rockies, who moved a game up on last-place Arizona in the NL West. It's the first time Colorado hasn't been in last place, either alone or shared, since July 13.
Lyles (7-3) gave up two runs and nine hits with one strikeout, consistently getting ground-ball outs in getting en route to his first win in eight starts since Aug. 6.
Chase Anderson (9-7), trying to become the fifth Diamondbacks rookie with at least 10 wins in a season, allowed six runs and nine hits in five innings.
The Rockies were leading 7-2 in the sixth when reliever Eury De La Rosa hit Justin Morneau with pitch to load the bases with one out. Cuddyer worked the count to 2-2 before driving De La Rosa's pitch deep into the left-field bleachers for his eighth career slam and first since May 30, 2012, against Houston. It was the fourth slam by a Rockies player this season and marked the 20th consecutive game in which Colorado has homered.
Cuddyer came up with the bases loaded again in the eighth and lined a three-run double to the gap in left-center. He's the first Rockies player with seven RBIs in a game since Jason Giambi on May 19, 2011, against Philadelphia.
Both Cuddyer and Rosario homered the night before in Colorado's 7-6 win over Arizona with Rosario delivering a two-run game-ender in the ninth.
Ynoa just missed an inside-the-park homer, settling for a two-run triple in the fifth when he was tagged out at home by Miguel Montero on a beautiful inning ending relay from second baseman Chris Owings.
Diamondbacks: RHP Bronson Arroyo, who was injured in mid-June and later underwent reconstructive elbow surgery, was transferred to the 60-day disabled list.
Diamondbacks:RHP Trevor Cahill (3-11) is slated to pitch Saturday night's Game 3 of a four game set against the Rockies. He's given up three or fewer runs in eight of his past 11 starts.
Rockies: RHP Eddie Butler (0-1) is scheduled to make his second career start Saturday night and first since taking the loss in his big league debut against the Dodgers on June 6. Butler was placed on the DL a day later because of right shoulder inflammation, missing five weeks and making two minor league rehab starts. He was recalled from Double-A Tulsa earlier this week.