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Emily Hollenbeck, a deep brain stimulation therapy patient, demonstrates an EEG device that records brain activity as she reacts to short videos at Mount Sinai’s “Q-Lab” in New York on Dec. 20, 2023. Dr. Brian Kopell, who directs Mount Sinai's Center for Neuromodulation, says in normal brains electrical activity reverberates unimpeded in all areas, in a sort of dance. In depression, the dancers get stuck within the brain’s emotional circuitry. DBS seems to “unstick the circuit,” he says, allowing the brain to do what it normally would. (AP Photo/Mary Conlon)
This brain scan image provided by Mount Sinai in 2024 shows the targeted sites for electrodes implanted in patient Emily Hollenbeck for use with deep brain stimulation therapy. Researchers say the treatment could eventually help many of the nearly 3 million Americans like her with depression that resists other treatments. (Mount Sinai via AP)
Emily Hollenbeck, a deep brain stimulation therapy patient, demonstrates how she makes circles in the air with her arms that are interpreted and projected as light on an interactive wall at Mount Sinai’s “Q-Lab” in New York on Dec. 20, 2023. Researchers use various methods to collect data as patients recover. Like many other patients, she moves her arms faster now that she’s doing better. (AP Photo/Mary Conlon)
Neuroimaging expert Ki Seung Choi explains how he uses brain scans to locate the exact spot in a particular patient where electrodes for deep brain stimulation therapy should be placed, at Mount Sinai West in New York on Dec. 20, 2023. Dr. Helen Mayberg, founding director of The Nash Family Center for Advanced Circuit Therapeutics, says, “Everybody’s brain is a little different, just like people’s eyes are a little further apart or a nose is a little bigger or smaller." (AP Photo/Mary Conlon)
Emily Hollenbeck stands for a portrait at the American Museum of Natural History's Rose Center in New York on Jan. 12, 2024. Hollenbeck lived with a deep, recurring depression she likened to a black hole, where gravity felt so strong and her limbs so heavy she could barely move. She was willing to try something extreme: Having electrodes implanted in her brain as part of an experimental therapy. (AP Photo/Mary Conlon)
Emily Hollenbeck, a deep brain stimulation therapy patient being treated for depression, stands for a portrait at the American Museum of Natural History's Rose Center in New York on Jan. 12, 2024. “When I was depressed, I couldn’t listen to music. It sounded and felt like I was listening to radio static,” she says. “Then on a sunny day in the summer, I was walking down the street listening to a song. I just felt this buoyancy, this, ‘Oh, I want to walk more, I want to go and do things!’ And I realized I’m getting better.” She only wishes the therapy had been there for her parents. (AP Photo/Mary Conlon)
A sample pacemaker-like device, used for deep brain stimulation therapy, and its electrodes which are implanted into a specific site in the brain are displayed at Mount Sinai West in New York on Dec. 20, 2023. The device controls the amount of electrical stimulation to the brain and delivers constant low-voltage pulses. Patient Emily Hollenbeck calls it “continuous Prozac.” (AP Photo/Mary Conlon)
Emily Hollenbeck stands for a portrait at the American Museum of Natural History's Rose Center in New York on Jan. 12, 2024. Hollenbeck, a deep brain stimulation patient being treated for depression, says, “The stress is pretty extreme at times, but I’m able to see and remember, even on a bodily level, that I’m going to be OK. ... If I hadn’t had DBS, I’m pretty sure I would not be alive today.” (AP Photo/Mary Conlon)
This series of PET brain scan images provided by Mount Sinai in 2024 shows changes in patient Emily Hollenbeck with deep brain stimulation therapy. Analyzing the brain activity of DBS patients, researchers found a unique pattern that reflects the recovery process. (Mount Sinai via AP)
Dr. Helen Mayberg, founding director of The Nash Family Center for Advanced Circuit Therapeutics, speaks to patient Emily Hollenbeck in her office at Mount Sinai West in New York on Dec. 20, 2023. Recent research by Mayberg and others published in the journal Nature showed it’s possible to provide a “readout” of how someone is doing at any given time. Analyzing the brain activity of deep brain stimulation patients, researchers found a unique pattern that reflects the recovery process. (AP Photo/Mary Conlon)