San Francisco 49ers quarterback Brock Purdy (13) hands off to running back Christian McCaffrey during the first half of an NFL football game against the Buffalo Bills in Orchard Park, N.Y., Sunday, Dec. 1, 2024. (AP Photo/Adrian Kraus)

San Francisco 49ers running back Christian McCaffrey, middle, runs against the Buffalo Bills during the first half of an NFL football game in Orchard Park, N.Y., Sunday, Dec. 1, 2024. (AP Photo/Gene J. Puskar)

San Francisco 49ers running back Isaac Guerendo, second from right, is congratulated by teammates after scoring against the Buffalo Bills during the second half of an NFL football game in Orchard Park, N.Y., Sunday, Dec. 1, 2024. (AP Photo/Gene J. Puskar)

San Francisco 49ers quarterback Brock Purdy speaks at a news conference after an NFL football game against the Buffalo Bills in Orchard Park, N.Y., Sunday, Dec. 1, 2024. (AP Photo/Adrian Kraus)

San Francisco 49ers running back Christian McCaffrey (23) runs against Buffalo Bills safety Taylor Rapp, bottom, during the first half of an NFL football game in Orchard Park, N.Y., Sunday, Dec. 1, 2024. (AP Photo/Adrian Kraus)

San Francisco 49ers quarterback Brock Purdy (13) passes against the Buffalo Bills during the second half of an NFL football game in Orchard Park, N.Y., Sunday, Dec. 1, 2024. (AP Photo/Adrian Kraus)

San Francisco 49ers running back Jordan Mason (24) runs against Buffalo Bills safety Damar Hamlin (3) during the second half of an NFL football game in Orchard Park, N.Y., Sunday, Dec. 1, 2024. (AP Photo/Adrian Kraus)