PASADENA, Calif. (AP) — PASADENA, Calif. (AP) — Arrowhead Research Corp. (ARWR) on Thursday reported a fiscal second-quarter loss of $125.3 million, after reporting a profit in the same period a year earlier.

On a per-share basis, the Pasadena, California-based company said it had a loss of $1.02.

The results missed Wall Street expectations. The average estimate of nine analysts surveyed by Zacks Investment Research was for a loss of 6 cents per share.

Arrowhead Research shares have dropped 19% since the beginning of the year. In the final minutes of trading on Thursday, shares hit $24.76, a fall of 39% in the last 12 months.

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This story was generated by Automated Insights (http://automatedinsights.com/ap) using data from Zacks Investment Research. Access a Zacks stock report on ARWR at https://www.zacks.com/ap/ARWR